PeptiSmile™ Advanced Peptide Toothpaste
Patent Pending
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PeptiSmile peptide toothpaste with tranexamic acid + peptides for a fresh, clean feel. Appearance-focused oral care in a convenient tube.
In stock
The complete story
Made to earn a place in your routine.
Oral care designed to keep up with the rest of your routine
You upgraded your skincare. You read labels. You know the difference between a formula with thoughtful actives and one filled with basic ingredients. So why should your toothpaste feel outdated?
Most toothpaste focuses on the surface. It helps clean teeth, freshen breath, and leave a minty finish. However, your mouth is more than enamel. Your gums and soft tissue face daily stress from brushing, food, drinks, and bacteria. That is why PeptiSmile™ takes a more complete approach to daily oral care.

PeptiSmile™ combines a multi-peptide complex with clean, purpose-selected ingredients. As a result, it still gives you the fresh, polished feeling you expect from toothpaste. At the same time, it brings a more advanced formula to your full oral care routine.
The Peptide Complex
Peptides are short chains of amino acids. In skincare, brands often use them to support the look and feel of soft tissue. Now, PeptiSmile™ brings an advanced peptide complex into a daily oral care formula.
Explore the full formula storyIngredients & formula details
Advanced Peptide Complex
PeptiSmile™ pairs a cosmetic multi-peptide blend with daily oral-care essentials for a clean, elevated brushing experience. The peptide complex is formulated for a refined approach to everyday gumline and soft-tissue care.
Palmitoyl Tetrapeptide-7
Palmitoyl Tetrapeptide-7 appears in many premium skincare formulas. Brands use it to support the appearance and resilience of soft tissue. With PeptiSmile™, this skincare-grade peptide moves into an oral care format, helping elevate your daily brushing routine.

The Supporting Ingredients
Great actives need the right base. Therefore, every ingredient in PeptiSmile™ has a clear purpose.
Tranexamic Acid
Tranexamic acid has a strong reputation across professional and cosmetic care. In PeptiSmile™, it supports a formula designed with the gumline in mind. It also helps create a more refined daily oral care experience.
Xylitol
Xylitol is a naturally derived sweetener often used in oral care. It gives PeptiSmile™ a clean taste without adding sugar.
Vitamin E
Vitamin E, also known as tocopherol, is a well-known antioxidant. It helps support formula stability while keeping the brushing experience gentle.
Dipotassium Glycyrrhizinate
Dipotassium glycyrrhizinate comes from licorice root. Cosmetic formulators often use it in products made for sensitive areas. As a result, it adds a soothing element to the overall formula.
What Makes PeptiSmile™ Different
Standard toothpaste:
Cleans the surface of teeth and leaves a mint flavor.
PeptiSmile™:
Combines daily cleaning with a peptide-powered formula for teeth, gums, and soft tissue care.
Standard toothpaste:
Uses a basic, mass-market formula.
PeptiSmile™:
Uses skincare-inspired peptides, xylitol, tranexamic acid, vitamin E, and other purpose-selected ingredients.
Standard toothpaste:
Often focuses on flavor first.
PeptiSmile™:
Focuses on a cleaner, more elevated brushing routine from start to finish.
Who It’s For
PeptiSmile™ is for people who care about the ingredients in every part of their routine.
It works well for anyone who already invests in advanced skincare, reads ingredient labels, and wants oral care that feels more intentional. It also fits people who want a daily toothpaste that goes beyond basic mint flavor and surface cleaning.
Clean Formula. No Compromises.
Built with:
Advanced peptide complex, tranexamic acid, xylitol, vitamin E, and dipotassium glycyrrhizinate.
Formulated without:
Parabens, harsh sulfates, and unnecessary fillers.
We make each batch in the USA under strict quality standards. Because of that, you get a consistent formula tube after tube.
How to Use
Apply a small amount to a soft-bristle toothbrush. Then, brush thoroughly for two minutes while paying close attention to the gumline. For best results, let the formula stay in contact with the mouth briefly before rinsing. Use twice daily, and pair it with regular flossing and routine dental checkups.
PeptiSmile™ Advanced Peptide Toothpaste
100ml / 3.4 fl oz
Modern peptide-powered oral care for people who expect more from everyday products.
Customer perspective
Real routines. Real reviews.
4 reviews for PeptiSmile™ Advanced Peptide Toothpaste
PeptiSmile™ Advanced Peptide Toothpaste

PeptiSmile feels like a nice upgrade from regular toothpaste. It’s easy to use daily, and I appreciate how fresh and clean my teeth feel afterward.
I really enjoy using this toothpaste. It has a pleasant taste and leaves my mouth feeling fresh and clean without being overpowering.
I’ve been using this twice a day and really like the overall brushing experience. The taste is pleasant without being overwhelming, and my mouth feels fresh and clean afterward.
PeptiSmile feels different from the usual toothpaste I’ve used. It leaves my mouth feeling really clean and fresh, and I like that the formula feels more thoughtfully designed than a basic everyday toothpaste.