PeptiSmile™ Advanced Peptide Toothpaste
Tranexamic acid + peptides for calmer gums and a brighter smile.
$24.99 — or Original price was: $24.99.$22.49Current price is: $22.49. / month
Why it works
PeptiSmile pairs tranexamic acid, a gum-care ingredient widely used in toothpastes across Asia, with a peptide blend that supports gum tissue. You brush it along the gum line twice a day, so it works right where your gums need it.
- 🌿Calmer, less swollen gumsTranexamic acid and licorice-root glycyrrhizinate are anti-inflammatory ingredients used in gum-care toothpastes.
- 🪥Less bleeding when you brushTranexamic acid is used in oral care in Asia to help reduce gum bleeding.
- 💪Healthier gumsA peptide blend supports healthy gum tissue.
- ✨Brighter smileTranexamic acid is known for evening out discoloration.
In stock
The complete story
Made to earn a place in your routine.
Oral care designed to keep up with the rest of your routine
You upgraded your skincare. You read labels. You know the difference between a formula with thoughtful actives and one filled with basic ingredients. So why should your toothpaste feel outdated?
Most toothpaste focuses on the surface. It helps clean teeth, freshen breath, and leave a minty finish. However, your mouth is more than enamel. Your gums and soft tissue face daily stress from brushing, food, drinks, and bacteria. That is why PeptiSmile™ takes a more complete approach to daily oral care.
PeptiSmile™ combines a multi-peptide complex with clean, purpose-selected ingredients. As a result, it still gives you the fresh, polished feeling you expect from toothpaste. At the same time, it brings a more advanced formula to your full oral care routine.
The Peptide Complex
Peptides are short chains of amino acids. In skincare, brands often use them to support the look and feel of soft tissue. Now, PeptiSmile™ brings an advanced peptide complex into a daily oral care formula.
Explore the full formula storyIngredients & formula details
Advanced Peptide Complex
PeptiSmile™ pairs a cosmetic multi-peptide blend with daily oral-care essentials for a clean, elevated brushing experience. The peptide complex is formulated for a refined approach to everyday gumline and soft-tissue care.
The Peptide Blend
PeptiSmile™ uses a peptide blend chosen to support the look and feel of the gumline. Skincare brands have used peptides for years to support the look and resilience of soft tissue. PeptiSmile™ brings that idea to your gum line, twice a day, every time you brush.
The Supporting Ingredients
Great actives need the right base. Therefore, every ingredient in PeptiSmile™ has a clear purpose.
Tranexamic Acid
Tranexamic acid is the lead named supporting active in PeptiSmile™. It is widely used in elevated oral-care formulas across Asia, especially in Japan, and is also well known in skincare for evening out the look of discoloration. In PeptiSmile, it sits alongside the peptide complex for a more intentional daily brush.
Xylitol
Xylitol is a naturally derived sweetener often used in oral care. It gives PeptiSmile™ a clean taste without adding sugar.
Vitamin E
Vitamin E, also known as tocopherol, is a well-known antioxidant. It helps support formula stability while keeping the brushing experience gentle.
Dipotassium Glycyrrhizinate
Dipotassium glycyrrhizinate comes from licorice root. It is a common gum-care ingredient in Japanese toothpastes, included here to help the mouth feel comfortable during and after brushing.
What Makes PeptiSmile™ Different
Standard toothpaste:
Cleans the surface of teeth and leaves a mint flavor.
PeptiSmile™:
Combines daily cleaning with a peptide-powered formula for teeth, gums, and soft tissue care.
Standard toothpaste:
Uses a basic, mass-market formula.
PeptiSmile™:
Uses skincare-inspired peptides, xylitol, tranexamic acid, vitamin E, and other purpose-selected ingredients.
Standard toothpaste:
Often focuses on flavor first.
PeptiSmile™:
Focuses on a cleaner, more elevated brushing routine from start to finish.
Who It’s For
PeptiSmile™ is for people who care about the ingredients in every part of their routine.
It works well for anyone who already invests in advanced skincare, reads ingredient labels, and wants oral care that feels more intentional. It also fits people who want a daily toothpaste that goes beyond basic mint flavor and surface cleaning.
Clean Formula. No Compromises.
Built with:
Advanced peptide complex, tranexamic acid, xylitol, vitamin E, and dipotassium glycyrrhizinate.
Formulated without:
Parabens, harsh sulfates, and unnecessary fillers.
We make each batch in the USA under strict quality standards. Because of that, you get a consistent formula tube after tube.
How to Use
Apply a small amount to a soft-bristle toothbrush. Then, brush thoroughly for two minutes while paying close attention to the gumline. For best results, let the formula stay in contact with the mouth briefly before rinsing. Use twice daily, and pair it with regular flossing and routine dental checkups.
100ml / 3.4 fl oz
Modern peptide-powered oral care for people who expect more from everyday products.
Customer perspective
Real routines. Real reviews.
13 reviews for PeptiSmile™ Advanced Peptide Toothpaste
PeptiSmile™ Advanced Peptide Toothpaste
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After using PeptiSmile for 2 months, my numbers really improved at the dentist. This was the only change in my oral care. Very happy and I am getting lots of compliments on my white teeth too.
This product has really helped me have much better checkups at the dentist. I also get compliments on how white my teeth are. I won’t go back to anything else.
I’ve really enjoyed using PeptiSmile. It leaves my mouth feeling clean and fresh after brushing, and I like that the flavor is pleasant without being too strong.
The taste is pleasant and not overly strong, and my mouth feels fresh after brushing. I also like knowing that the formula includes peptides, xylitol, vitamin E, and other thoughtfully selected ingredients.
I’ve really enjoyed adding PeptiSmile to my daily routine. It gives me that clean, fresh feeling I expect from toothpaste, but the formula feels a little more elevated than what I normally use.