EleveXo® S – Skin Renewal Formula
$695.00
EleveXo® S – Skin Renewal Formula is a professional peptide skin formula for aesthetic practices. Biomimetic peptides, Copper Tripeptide-1, Acetyl Hexapeptide-8, PDRN and low-molecular-weight hyaluronic acid work together for smoother, firmer-looking, hydrated skin and a softer look to expression lines.
- Professional-use formula for aesthetic practices and medical spas
- Pairs with in-clinic microneedling such as the NanoPen® Pro™
- Suggested professional protocol: every 14 days
In stock
The complete story
Made to earn a place in your routine.
The Science Behind EleveXo® S – Skin Renewal Formula
Skin aging develops as cell turnover slows, collagen levels drop, blood flow decreases, and the skin barrier weakens. EleveXo® S – Skin Renewal Formula addresses these connected changes through a complete, multi-pathway approach designed to support visible skin renewal and long-term strength.
Instead of treating one concern at a time, EleveXo® S works across cellular, structural, and vascular pathways. Because of this, it helps create conditions where skin can renew more efficiently and maintain a smoother, firmer appearance over time.
Growth Factors That Support Skin Regeneration
Growth factors act as natural signals that guide skin cells to repair, rebuild, and renew tissue. Therefore, EleveXo® S – Skin Renewal Formula includes five well-studied growth factors that work together to support firm, healthy, youthful-looking skin.
EGF (sh-Oligopeptide-1)
Epidermal Growth Factor binds to EGFR receptors on key skin cells, which encourages renewal and movement. As a result, topical EGF supports faster surface turnover, smoother texture, and improved tone. In addition, it boosts fibroblast activity and collagen output, helping reduce visible signs of aging.
Explore the full formula storyIngredients & formula details
IGF-1 (sh-Oligopeptide-2)
Insulin-Like Growth Factor-1 declines with age and often leads to thinner, less resilient skin. By adding a biomimetic form, EleveXo® S helps support fibroblast function and strengthen the skin’s support structure, which improves overall density.
VEGFA (sh-Polypeptide-9)
Vascular Endothelial Growth Factor A supports healthy blood flow by encouraging new vessel growth. As circulation improves, oxygen and nutrients reach the skin more easily, which helps maintain collagen turnover and cell activity.
aFGF (sh-Polypeptide-11)
Acidic Fibroblast Growth Factor plays an important role in tissue repair. Within aesthetic care, it supports fibroblast growth and works alongside other growth factors to promote collagen and elastin production.
bFGF (sh-Polypeptide-1)
Basic Fibroblast Growth Factor increases fibroblast activity and supports the production of collagen and moisture-binding compounds. Together, these effects help strengthen the skin structure and improve firmness.
Biomimetic Peptides That Enhance Natural Repair
Biomimetic peptides in EleveXo® S – Skin Renewal Formula mirror the skin’s natural signals. As a result, they help support repair, balance, and long-term skin stability.
copper peptide (Copper Tripeptide-1)
This well-known peptide supports collagen, elastin, and hydration molecules, which helps improve firmness and skin vitality.
AHP (Acetyl Hexapeptide-8)
Often called a smoothing peptide, AHP helps soften the look of expression lines by reducing repeated muscle tension at the skin surface.
Phyto-NEP (Caffeoyl sh-Decapeptide-9)
This plant-based peptide supports antioxidant defense while also helping calm irritation and promote smoother skin.
Supporting Actives for Hydration and Repair
These supporting ingredients work with the growth factors and peptides to create ideal conditions for renewal.
Low-Molecular-Weight Hyaluronic Acid
This form absorbs efficiently to bind moisture, improve elasticity, and support a hydrated, resilient skin layer.
Adenosine
Adenosine interacts with skin receptors to support collagen production and healthy blood flow. Additionally, research links it to visible improvement in fine lines.
PDRN (Polydeoxyribonucleotide)
This regenerative compound supports key skin cells while promoting blood vessel growth and tissue repair. Because of this, it helps prepare the skin for stronger renewal.
How EleveXo® S – Skin Renewal Formula Works
Together, these ingredients support several core elements of youthful skin:
- Increased collagen and elastin production
- Faster skin renewal
- Improved hydration and barrier strength
- Better blood flow
- Reduced appearance of expression lines
Who EleveXo® S Is Designed For
EleveXo® S – Skin Renewal Formula is intended for professional use in:
- Dermatology and anti-aging practices
- Medical spas with licensed providers
- Post-procedure recovery care
- Combination treatments with microneedling, RF, or laser therapies
Clinical Use and Integration
- Suggested use: Apply every 14 days as a standalone treatment or alongside aesthetic procedures
- Visible improvements: Often seen within 4–8 weeks, with continued benefits over time
- Professional guidance: Recommended to ensure proper patient selection
- Formulation note: No systemic effects or permanent treatment claims
EleveXo S Skin Renewal Formula FAQ
What is EleveXo S?
EleveXo® S – Skin Renewal Formula is a professional skin formula that combines biomimetic peptides (sh-oligopeptides and sh-polypeptides), Copper Tripeptide-1, Acetyl Hexapeptide-8, PDRN, adenosine and low-molecular-weight hyaluronic acid for smoother, firmer-looking, hydrated skin. $695.
Who is EleveXo S for?
It is designed for professional use by aesthetic practices and medical spas with licensed providers, including alongside in-clinic microneedling.
How often is it used?
The suggested professional protocol is every 14 days, as a standalone step or alongside aesthetic procedures.
Does Simple Cosmetics sell a microneedling pen to pair with it?
Yes. The NanoPen® Pro™ microneedling pen and its replacement cartridges are in the same professional collection.
Related: EleveXo® H scalp formula · NanoPen Pro · Professional collection
Customer perspective
Real routines. Real reviews.
8 reviews for EleveXo® S – Skin Renewal Formula
EleveXo® S – Skin Renewal Formula
Optional. Your answers may appear with your review to help others with similar skin.
I’ve been enjoying this formula as part of my regular skincare routine. It layers nicely with my other products and leaves my skin feeling smooth, hydrated, and well cared for.
EleveXo S has a really nice texture and feels comfortable on my skin. It applies easily and leaves my complexion feeling soft and refreshed without a heavy finish.
This has a really nice texture and applies easily without feeling heavy. I like how polished and smooth my skin looks after incorporating it into my routine.
I’ve been enjoying EleveXo S as part of my skincare routine. The formula feels smooth and comfortable, and my skin looks refreshed and feels nicely moisturized after using it.
This formula has become one of my favorites. I like how polished my skin looks after using it, and the texture makes it easy to layer with the rest of my skincare products. It feels like a thoughtful addition to my routine.